Keep Going: Progress is possible.

Where you're born shouldn't determine whether you survive being born. Yet today, the gap between maternal and child mortality rates in the global South and North remains stark — not because we lack solutions, but because we haven't prioritized them. We're working to close that gap for good, with a goal of halving child mortality again by 2045.

Vaccines remain the single best investment in global health. We're funding discovery, scale, and delivery of immunizations that protect children before and after birth. And since malnutrition underlies half of all child deaths, we're funding research that could reshape how the world addresses it.

A new $2.5 billion commitment targets five chronically neglected areas of women's health: obstetric and maternal care, nutrition during pregnancy, gynecological health, contraceptive options, and STI treatment. Conditions like pre-eclampsia — common, poorly understood, and often deadly in low-resource settings — are finally getting the research attention they deserve.

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By 2045, we believe polio and malaria can be eradicated, and TB and HIV brought under control as manageable conditions. That's not optimism for its own sake — it's where the science and the momentum point, if we stay focused.

New tools are in the pipeline, including a TB vaccine candidate that could be transformative for communities where the disease has touched nearly every family. The challenge now is ensuring innovations reach the people who need them, not just those with the easiest access.

In sub-Saharan Africa, a shortage of nearly six million health workers means professionals are stretched far too thin. Through partnerships and innovations, we're bringing AI tools to 1,000 primary health clinics across the region — supporting everything from patient intake to follow-up care, helping health workers deliver better services to more people.

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For most people in South Asia and sub-Saharan Africa, prosperity starts on a small farm. Agriculture is two to three times more effective at reducing poverty than growth in any other sector, with the greatest gains going to the poorest households. So, we recently committed $1.4 billion over four years to help millions of smallholder farmers adapt to a changing climate — through better seeds, tools, and climate-resilient crops.

In the United States, economic opportunity runs through education. Students who pass Algebra 1 by 9th grade are significantly more likely to graduate, pursue college, and earn a family-sustaining wage — so that's where we've focused our math investments.

We're also funding the connections between K–12, higher education, and careers, because getting into college isn't enough if students don't have the support to finish and find opportunity on the other side.

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