As a leader in research and development, South Africa has the potential to help advance progress throughout the rest of Africa and the world.

Addressing South Africa's Greatest Needs

South Africa is a country with global influence that has both significant challenges, including high rates of HIV and TB, and critical assets, such as a world-renowned scientific and research community. Since making our first grants here in 1999, we have been committed to addressing these issues and investing in its promising future.

We are working with South Africa to apply its clout, research, and solutions to address its greatest needs. Our current investments to more than 100 organizations are focused on four main goals:

  1. Discover and develop new drugs, diagnostics, and vaccines for HIV and TB. Although South Africa comprises less than 1 percent of the global population, it contributes to 18 percent of the world’s HIV infections and HIV-related deaths, as well as 6 percent of the world’s TB infections and 2.5 percent of global TB-related deaths.
  2. Support the effective delivery of proven HIV prevention and treatment plans, as well as TB operations and implementation research.
  3. Collaborate with the South African government on shared goals for global health and development.
  4. Support limited research, provide technical assistance and program support for other priorities including family health, agriculture, water sanitation, and hygiene.