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Novel Artemisinin Manufacturing Technologies Request for Proposal

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Open Date: Thursday, July 6th, 2017 at 12:00PM (PST)

First Closing Date: Friday, August 4th, 2017 at 5:00PM (PST)

Final Deadline: Friday, September 29th at 5:00PM (PST)

Overview

The goal of this project is to develop novel approaches through the proof of concept stage for the manufacturing of artemisinin and/or its precursors as a starting material or intermediate to prepare artemisinin-based active pharmaceutical ingredients. These approaches should demonstrate the potential (with a high probability of success) to meet aggressive cost targets when being practiced at commercial scale. It is anticipated (but not guaranteed) that successful awardees will be requested to submit a further proposal for additional development work, scale-up to pilot scale and generation of the necessary materials (e.g. cell banks) and technology transfer packages to enable manufacturing at multiple existing manufacturing facilities. It is likely that multiple responders will require partnering to meet the RFP objectives and to help facilitate this, the Foundation will be scheduling two virtual proposer events. Interested parties are requested to complete and submit a six page Concept Memorandum by the deadlines outlined below and in the attached RFP.

Timeline

Thursday July 6th, 2017 at 12 pm PST: Request Announced
Wednesday, July 19th from 8am to 9am PST: Q&A Teleconference
Friday, August 4th, 2017 at 5 pm PST: First Closing Date for Concept Memorandum submissions*
Monday, August 7th, 2017 at 5pm PST: Deadline to sign-up for Virtual Partnering Events
Wednesday, August 9th, 2017 at 5pm PST: Submission of Virtual Partnering Event Templates
Tuesday, August 15th from 8am to 9am PST: First Virtual Partnering Event
Tuesday, August 29th from 4pm to 5pm PST: Second Virtual Partnering Event - CANCELLED 
Friday, September 29th at 5 pm PST: Deadline to submit the completed Concept Memo Template*

*There will be two “closing” dates to accommodate 1) potential rapid responses and awards for responders that can meet the tighter timelines and 2) to allow for more time where it is required for partnering and/or the crafting of responses.

How to Apply

Please submit all documents directly to NovelARTrfp@gatesfoundation.org. Your submission should include only the completed Concept Memorandum. Other attachments, including cover letters and supplemental information will not be accepted or reviewed.

Download the RFP Guidelines PDF.

Download the Concept Memorandum Template.

Download the Frequently Asked Questions PDF.

Questions

Questions received through the RFP mailbox, NovelARTrfp@gatesfoundation.org, will be responded to in writing at the end of the week in which they are received. To attend the Virtual Partnering Event, please sign up via email, NovelARTrfp@gatesfoundation.org by August 7th, 2017 at 5pm PST. Additionally, please reference the Frequently Asked Questions PDF for further guidance.

 

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